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Sara Gottfried MD
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Posts Tagged ‘disease care’

What is Personalized Medicine? A New Way Of Looking at Health Care

By Jeffrey Bland PhD | April 5, 2014
What is Personalized Medical Way_ A New Though of Looking at Health Care

Greetings to you—the women, the men, the health warriors and advocates—who follow my good friend and colleague, Sara Gottfried, MD. I am Dr. Jeff Bland and there is a very good chance this is the first time you have heard my name (and that’s okay). But I’m not new on the scene, believe me—the medicine…

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PRAISE

“For the first time in my adult life I feel that I have gained control over food. I feel healthier, look better and have gained an interest in making sure that what I am putting into my body is the best it can be. And I lost 10 pounds in all the right places.”

– Janice Lunde, Dr. Sara’s Detox Challenge Participant

“Dr. Sara is the height of excellence! She is incredibly knowledgeable and gives very generously of her time. I feel so blessed to have been able to work with her.”

– Yvonne Varah

“You don’t have to settle for being stressed out, binging on sugar and chocolate, and aging prematurely. Stop blaming yourself and step into sacred action. It’s your birthright. You can have the joyous, mission-driven life you want, and Dr. Sara is here to show us how.”

– Marci Shimoff, New York Times Bestselling Author of Happy for No Reason and Love for No Reason

“Dr. Gottfried offers powerful and effective tools for addressing the most difficult health issues facing women and men today. She is warm and kind and has so much experience to draw upon, it’s inspiring. Thank you Dr. S!”

– Cassandra Mick

“Dr. Sara Gottfried is a modern-day healer goddess if ever there was one, and she also happens to be a Harvard Medical School graduate and rigorous physician-scientist.”

– Christiane Northrup MD, author of Women’s Bodies, Women’s Wisdom

“Dr. Gottfried’s book and detox came at a time when I was ready to give in to old age. Hot flashes, low energy and libido, weight gain, increasing blood pressure and cholesterol levels were unacceptable to me. I now know that hormone levels and what I eat are a huge influence on how I feel and look. To now be able to control something that was out of control is empowering…”

Cheryl V., Dr. Sara’s Detox Challenge Participant

“My health coach told me about your book and I took the [hormone] test, and lo and behold, I found I was a mess, hormonally speaking. Now I’m getting on track and I love your videos and your book. I feel like I’m getting my life back again, when not long ago I truly thought I was losing it!”

-Tracy, Registered Nurse

“You don’t have to accept the hormonal hell of being tired, stressed, overweight, and never in the mood for sex as you grow older. In her fabulous new book, the brilliant Dr. Gottfried gives you an effective, easy-to-follow plan to balance your hormones and become lean, energetic, and loving life again. Stop settling and reclaim your sexy!”

–JJ Virgin, Author of Six Weeks to Sleeveless and Sexy and The Virgin Diet

“I lost 10 lbs., reset my hormones and metabolism and eliminated my sugar cravings! I have also found that I respond to stress much differently, I feel it, notice it and move on from it. Stress no longer has a grip on me. Dr. Sara’s conference calls and detox information was invaluable. I am so grateful for this program. Thank you Dr. Sara!”

–Sophia, Dr. Sara’s Detox Challenge Participant

“The Hormone Cure is the playbook for your mojo, your mind, and your bootie. With every chapter I thought, ‘So THAT’s how that works.’ I wanted to call every girlfriend and give them the goods on how to glow… now and always.”

-Danielle LaPorte, Author of The Fire Starter Sessions and The Desire Map

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In the previous Basic Insulin Pathway post, I desc In the previous Basic Insulin Pathway post, I described insulin as the KEY needed to unlock the door of cells to allow glucose to enter—so that glucose can be used as fuel for muscles and for energy needs of cells. 🔸️ What happens when that lock is jammed? Insulin receptors in the liver and muscle become RESISTANT to insulin and the key no longer fits in the lock. Excess glucose may be deposited as fat. 🔸️ Once more, I want to add that this is a very simplified version of Insulin Resistance, or Insulin Block. There are many other factors involved that make the process more complex and consequently, make weight loss (particularly visceral fat loss) more complicated. More on that to come. 🔸️ For now, let’s focus on simple insulin resistance. 🔸️ How does the cell’s lock get jammed so that the insulin key no longer works? 🔸️ When there is a rise in blood glucose levels from too much glucose intake (combined often with excess stress, lack of sleep, and insufficient exercise, among other factors) and receptors start to struggle, insulin levels rise accordingly. The pancreas works hard to keep up with the demand for insulin. 🔸️ Insulin shouts LOUDER. Imagine insulin banging on the door of the cell, like an irate neighbor, who complains about everything. In the beginning, the cell is willing to listen and eventually opens the door. But soon the cell can’t be bothered to get up and open the door anymore. The receptor is becoming jammed, or increasingly numb to the voice of insulin. 🔸 The pancreas thinks that making even MORE insulin will fix the problem. Then a vicious cycle is off and running. Insulin keeps knocking more and more loudly. The cell ignores the knocking and even puts in earplugs so it can’t hear the knocking. This is Insulin Resistance. The cells become numb to insulin and glucose levels in the blood continue to rise. Late in the process, cells that are still willing to open the door are fat cells. Excess glucose may be stored as fat. The increased levels of insulin are now promoting fat STORAGE over fat BURNING. Adipose tissue EXPANDS to accommodate the excess glucose and we gain weight, especially fat in the belly and in/around abdominal organs.
INSULIN: When you have a basic idea of how insulin INSULIN: When you have a basic idea of how insulin works in your body, then you are on the right path to making changes to your diet and lifestyle—and figuring out what works for YOU. 🔸️ This is the first in a series of posts that aims to explain the basic insulin pathway, how it regulates blood sugar, how your cells become resistant to insulin (Insulin Block) as well as the crosstalk that happens between insulin and various hormones, including testosterone and estrogen. 🔸️ I recognize that are so many factors that influence or interfere with this insulin pathway and how it regulates blood sugar, including perceived stress, activity level and fitness, as well as your microbiome. 🔸️ But let’s start with the basics and build on them from there. Make sure to save these posts for future reference. ⏩BASIC INSULIN PATHWAY⏩ Insulin is a hormone in charge of how you derive energy from the foods you eat. Your body runs on glucose, and insulin is one of the master switches. The pancreas secretes insulin. Its release is finely calibrated to produce just the right amount so that glucose can be extracted from food in your gut, sent into your bloodstream, and then driven into cells, particularly the fat, muscle, and liver cells. The glucose level in your blood returns to normal. 🔸️ How does insulin transport glucose into the cells? Your cells have receptors, which respond to specific hormones. Receptors are like locks on a door. Receptors for insulin are present in target cells, primarily, liver, muscle and fat cells. Insulin is the KEY that fits into the lock (receptor) to open the door to allow glucose to enter into these cells. 🔸️ Once insulin gets glucose inside the cell, the cell can get busy with crucial tasks such as growth, movement, and repair. Glucose is stored in the cells of the liver and muscles as glycogen—a storage form of glucose that can be broken down readily when you need fuel. 🔸️ I have added some previous posts that address optimal glucose levels to my Stories so you can refer to those for more information. 🔸️ What other questions do you have for me regarding insulin?
My goal for all of you is to architect the best po My goal for all of you is to architect the best possible health. Yet, I know how hard it is when you are struggling with weight, body image, and hormonal imbalances that throw obstacles in the path to reaching your full potential. When taking steps to change how you eat, move, think and supplement so you can feel whole and alive, I ask you to be gentle and to start with loving and kind words toward yourself. . Tomorrow is Valentine's Day❤ Take this day to love yourself.  If you follow me here, it is my sincere hope that you’ve learned by now, many of your health issues don’t stem from the fact that you are "weak" or "lazy" or have no willpower. Most likely your body needs recalibration. Say no to blaming yourself, and put your energy into the positive direction of your own growth and healing. . Here is one of my favorite loving-kindness meditations from my book THE HORMONE RESET DIET 🔸️ Sit comfortably and without distraction. Take 5 deep breaths with slow, long, and full exhalations. Repeat the following mantra as many times as you need to in order to feel complete: 🔸️ May I be filled with loving-kindness. May I be happy. May I be full of grace. May I be healthy. May I live with ease. 🔸️ When you are ready, send the same blessings to a loved one. 🔸️ May YOU be filled with loving-kindness, etc. 🔸️ Recite the mantra once more for yourself. 🔸️ Finally, add a last phase of the meditation to someone you hold anger or resentment toward. 🙏 Practice this and let me know if it helps you. Happy Valentine's Day ❤ #valentine #galentinesday #valentines #valentinesday
My clinical experience has taught me that resettin My clinical experience has taught me that resetting your insulin may be the single most important action you can take to lose excess fat and improve your health. In many cases, insulin resistance is reversible. The first place to start is to reduce or give up refined sugar. However, it is important to keep in mind what you are up against. Sugar is powerfully addictive. Hyperpalatable foods with high levels of sugar and fat are the most addictive, leading to craving, bingeing, and withdrawal in rats, similar to what we see with addictive drugs. (Avena, 2010, Study of Food Addiction Using Animal Models of Binge Eating.) . I put sugar in the same category as addictive drugs like crack or heroin. Take the iconic chocolate sandwich cookie, for example. One study from Connecticut showed that rats fed America’s favorite cookie liked it as much as cocaine and morphine. . When the rats ate the chocolate sandwich cookies, the pleasure center of their brains, the nucleus accumbens, lit up like a Christmas tree— the same area in the brain that lights up with cocaine. Sugar and cocaine both stimulate the addictive part of the brain with a neurotransmitter called dopamine, known for its role in pleasure and satisfaction. Rats in the study even broke open the cookie to eat the sugary middle first. . Even if you feel totally out of control with your sugar cravings, there is a path to recovery. With my books THE HORMONE CURE and THE HORMONE RESET DIET as well as my online hormone reset programs, I have helped many women change their relationship with sugar and gain peace with food. Is it one-size-fits-all? No. Does it work for all women? No. Is addictive behavior with sugar easy to solve? No. However, when you cut out sugar, your cravings usually improve and your insulin may improve, some quicker than others depending on your starting point and other complicating factors such as PCOS. . Who has helped you improve your sugar intake? How did you do it?
Are you enjoying my PCOS video series? Do you find Are you enjoying my PCOS video series? Do you find it helpful? I created a PCOS Highlights recap to make sure you can easily find these videos again or share them with others. In addition to the videos, you will also find the slides I mentioned in my video as well as previous posts that talk about high androgen levels in PCOS as well as supplements to control blood sugar. What other questions do you have for me? Tag a #pcoswarrior who needs this information 🔽🔽 . . . . #pcos #pcossucks #pcosawareness #pcossupport #pcosjourney #pcosdiet #pcossuccessstory #pcossuccess #pcosweightloss #pcosawareness #pcosfighter #pcoslife #pcosfood  #pcosnutrition #pcosfitness #pcosweightlossjourney #pcoscommunity #pcosproblems #homoneexpert #hormonalimbalance #hormoneimbalance #thehormonecure #thehormoneresetdiet #precisionmedicine #functionalmedicine #integrativemedicine
While I agree that hormonal birth control doesn’ While I agree that hormonal birth control doesn’t address the root cause, as an OB/GYN I’d add that we don’t completely understand the root cause of Polycystic Ovary Syndrome (PCOS) in all women, especially in those at a normal weight. The problem in PCOS is that 75-80% of patients have high insulin, not 100%. So not all women with PCOS have insulin block or resistance, where their cells become numb to the insulin signal, like a text in the body. Research shows that 59% of normal weight women are insulin resistant, 78% of overweight women, and 94% of obese women (Tosi et al., 2017, based on euglycemic clamp). The high insulin in the blood drives up androgens like testosterone. But what is happening in women who don’t have insulin block? Or women with “nonhyperandrogenic” PCOS, who have irregular periods (every 35 days or longer) and multiple small (<1cm) cysts on ultrasound? We don’t really know. Dr. Brighten is probably correct in assuming that the root cause is metabolic and/or inflammatory since they are final common pathways for most conditions, but we haven’t yet proven this definitively in all PCOS patients. Please check out @drjolenebrighten ! How can we address the root cause if we don’t understand what it is in 25-30% of women? In functional medicine, we address PCOS with a systems biology approach—that includes the hormonal system, detoxification/biotransformation , energy metabolism, immune and inflammation, gut/microbiome health, structure, and transport (e.g. cardiovascular system). Even though more research is needed to elucidate the root cause in more women with PCOS, we can still apply systems biology to help women rebalance their hormones with evidence-based and personalized therapeutic lifestyle changes and feel better. I know we all want easy answers with problems like PCOS, but we need to be careful to understand the whole truth and not oversimplify—which can be challenging on social media! #repost @drjolenebrighten ❤️ #pcos #pcosawareness #pcossupport #pcosnutrition #functionalmedicine #precisionmedicine #personalizedmedicine #rootcause #rootcauseanalysis #hormones #hormonebalance #hormoneimbalance #insulin #insulinresistance #testosterone
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